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Facilities and equipment in each of the departments contributing to the Interdisciplinary Ph.D. in Biology Program are summarized below.
Department of Biology: The Department of Biology occupies laboratory and office spaces in the Woodward Building (dedicated Fall 2005). Our laboratories are well equipped with instrumentation needed for a wide range of molecular, microbial and organ and organismal research. These include low speed, high speed and ultra centrifuges, scintillation and gamma counters, tissue culture facilities, spectrophotometers, thermal cyclers, gel analysis hardware and software, standard upright and inverted microscopes with fluorescence, in vivo video microscopes with analysis software for quantitative fluorescence, confocal microscope, complete equipment for physiologic monitoring, cryostat, HPLC, FACS, gas chromatograph, etc. It also includes a state-of-the-art vivarium.
Core Facilities : The core facilities available include an Imaging Core Facility and a DNA Sequencing Core Facility as well as a Microarray Core Facility at CMC with workstations in the Cameron Applied Research Center.
The Carolinas Medical Center : The Cannon Research Center is a 58,000 square foot building which provides state-of-the-art research laboratories in a central facility for clinical and basic science research. Available for use are bioreactors, a press for preparation of polymer matrices for tissue engineering, two flow cytometers (including one equipped for cell sorting), isolated heart perfusion systems and systems for analysis and recording, a Coulter counter, numerous tissue culture hoods and incubators, centrifuges, ultracentrifuges, balances, high performance liquid chromatography, ELISA readers, scintillation and gamma counters, PCR apparatus and phosphor imager, fluorimeters, multi-channel high speed data acquisition systems for displacement, pressure temperature and deformation sensors for bone strength analysis, equipment for experimental in vitro fertilization studies, microwave and direct currents tomographs, electrophysiology computerized mapping systems, optic and laser light sources, fiber optics and catheter systems and analytical tools, ultra low freezers, refrigerator freezers, microscopes (light, fluorescent and inverted), a transmission electron microscope, a complete histology core laboratory, and extensive computer support.
Department of Chemistry : Program faculty from the Department of Chemistry occupy over 5000 square feet of laboratory space located in the Physical Sciences building and the adjacent Cameron Applied Research Center. A computational Chemistry Lab is equipped with 8 Indigo 2 SGI Work Stations. A lab for Scanning Tunneling Microscopy in Cameron is occupied by one of the Chemistry faculty and there are 3 small labs in the Cameron Center for the Regional Analytical Chemistry Laboratory. Major items of research equipment include 300 MHz NMR spectrometers, a GC/MSD, a single crystal X-ray diffractometer, a GC/FTIR spectrometer, as well as GCs, HPLCs, Capillary electrophoresis, FTIR, UV and Spectrofluorometers.
Department of Physics: Facilities and Equipment at the Department of Physics include: 6 laboratories (2310 square feet) Unix, Sun workstations, and Personal Computers; Optics Laboratories for high resolution imaging, spectroscopy, nearfield scanning optical microscopy, and fiber sensor development.
Department of Mechanical Engineering and Engineering Science: Facilities and equipment available to the proposed program include: videomicroscopy system capable of cryo, fluorescence, polarized light, DIC, and brightfield microscopy; image analysis software, a differential scanning calorimetry system for materials characterization, and a laminar flow hood for tissue culture. The biomedical engineers that are part of the program faculty have laboratory space in the Woodward Building with the Biology Faculty. However, they also have offices in the new Mechanical Engineering Building on coampus. In addition, the Center for Precision Metrology of the Department of Mechanical Engineering is also housed in this new Building. The available facilities include an excellent machine shop and electronics shop and clean room for microfabrication. Most relevant to the program is an extensive commitment to microscopic imaging, including Scanning Probe Microscopy which incorporates atomic force and scanning tunneling capabilities. Computing facilities are also available for processing and analyzing images of biological specimens.
The Department of Electrical and Computer Engineering , which houses the Biosensors group also has extensive facilities pertinent to the proposed program. These include a scanning electron microscope, FT IR and NMR systems, a mass spectrometer, x-ray diffractometer, video optical imaging setup with image processing software.
The Department of Civil Engineering has facilities and equipment that complement the holdings in the Biology Ph.D. program. These include a gas chromatograph, video microscopy, analytical equipment for water quality (physical and chemical) testing, a UV-vis spectrophotometer, and UV disinfection equipment.
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