Zoology, Science and the Scientific Method (Chap. 1)

 

I.  Zoology

 

II.  Science

 

III.  Scientific Method

            A.  The process:  the hypothetico-deductive method

            B.  Example:  Peppered moth of England.

 

IV.  Creationism science (intelligent design)

 

 

 

Survey of Major Animal Taxa

 

 

I.  Protista (animal-like unicellular organisms)

            A.  Phylum Sarcomastigophora

                        1.  Subphylum Mastigophora

                        2.  Subphylum Sarcodina

            B.  Phylum Apicomplexa

            C.  Phylum Ciliophora

 

II.  Metazoa (multicellular animals)

            A.  Phylum Porifera

            B.  Phylum Cnidaria

                        1.  Class Hydrozoa

                        2.  Class Scyphozoa

                        3.  Class Anthozoa

            C.  Phylum Platyhelminthes

                        1.  Class Turbellaria

                        2.  Class Trematoda

                        3.  Class Cestoda

            D.  Phylum Nematoda

            E.  Phylum Mollusca

                        1.  Class Gastropoda

                        2.  Class Bivalvia

                        3.  Class Cephalopoda

            F.  Phylum Annelida

                        1.  Class Polychaeta

                        2.  Class Oligochaeta

                        3.  Class Hirudinea

            G.  Phylum Arthropoda

                        1.  Subphylum Chelicerata

                                    a.  Class Merostomata

                                    b.  Class Arachnida

                        2.  Subphylum Crustacea

                        3.  Subphylum Uniramia

                                    a.  Class Chilopoda

                                    b.  Class Diplopoda

                                    c.  Class Insecta

            H.  Phylum Echinodermata

                        1.  Class Asteroidea

                        2.  Class Ophiuroidea

                        3.  Class Echinoidea

                        4.  Class Holothuroidea

                        5.  Class Crinoidea

            I.  Phylum Chordata

                        1.  Subphylum Vertebrata

                                    a.  Class Agnatha

                                    b.  Class Chondrichthyes

                                    c.  Class Osteichthyes

                                    d.  Class Amphibia

                                    e.  Class Reptilia

                                    f.  Class Aves

                                    g.  Class Mammalia

 

 

Evolution (Chap. 6)

I.  Introduction

 

II.  Evidence for Evolutionary Change

               A.  Fossils

               B.  Homologies

                        1.  anatomical:  ex:  forelimb of vertebrates (p. 111)

                                                  ex:  mouthparts of insects (p. 416)

                                                  ex:  vestigial organs

                        2.  embryological  (p. 168)

                        3.  biochemical

 

 

III.  Evolution and Genetics:  Neo-Darwinism and the synthetic theory.

               A.  Definition of Evolution

               B.  Levels of evolutionary change:

                        1.  Microevolution

                        2.  Macroevolution

 

IV.  Microevolution

               A.  The Gene Pool

                        1.  sources of genetic variability

                        2.  genetic equilibrium

 

               B.  Factors that change allelic frequencies (disturb genetic equilibrium)

                        1.  Natural selection

                                    a.  The argument:

                                    b.  Example:  loop of Henle

                                    c.  Types of evolutionary responses to natural selection

                                    d.  Characteristics of Natural Selection:        

                        2.  Genetic Drift

                                    a.  bottleneck effect

                                    b.  founder effect

                        3.  Nonrandom Mating

                        4.  Migration

                        5.  Interaction of Natural Selection, Genetic Drift and Migration

 

C.  Speciation

                        1.  definition of species

                        2.  reproductive barriers

                                    a.  premating barriers

b.  postmating barriers

                        3.  types of speciation

                                    a.  allopatric speciation

                                                -- vicariant speciation

                                                -- founder event 

                                    b.  sympatric speciation

                        4.  adaptive radiation

 

V.  Macroevolution

               Aspecies selection

               B.  mass extinctions 

 

VI.  Rate and Patterns of Evolutionary Change (of speciation)

               A.  Gradualism

               B.  Punctuated Equilibrium

 

 

 

Developmental Patterns and Body Plans

(Chap. 8, pp. 156-163; Chap. 9 pp. 179-184)

 

I.  Levels of Organization

            A.  Protoplasmic grade

            B.  Cellular grade

            C.  Tissue grade

                        1.  primary tissue (germ) layers

                        2.  tissue types

            D.  Organ grade

            E.  Organ system grade

 

II.  Symmetry

            A.  Radial

            B.  Bilateral

 

III.  Early Embryological Development

 

            A.  Cleavage Patterns

                        1.  no distinct pattern

                        2.  spiral cleavage

                        3.  radial cleavage

 

            B.  Developmental fate of early blastomeres

                        1.  mosaic (determinate) development

                        2.  regulative (indeterminate) development

 

            C.  Formation of Germ Layers, Body Openings and Gut

                        1.  Germ layers

                                    a.  ectoderm and endoderm

                                    b.  origins of mesoderm

 

                        2.  Body Openings and Gut

                                    a.  incomplete gut:  one body opening

                                    b.  complete gut:  two body openings

                                                -- Protostomes

                                                -- Deuterostomes

 

            D.  Formation of Body Cavities

                        1.  Acoelomic

                        2.  Pseudocoelomic

                        3.  Schizocoelomic

                        4.  Enterocoelomic

 

            E.  Protostome vs. Deuterostome Development

 

 

Protostome

 

Deuterostome

Cleavage pattern

 

spiral

radial

Developmental fate of early blastomeres

 

mosaic

regulative

Fate of blastopore

 

Becomes mouth

Becomes anus

Origin of mesoderm

 

From 4d cell

From outpouchings of archenteron

Body cavity

 

Acoelomic; Pseudocoelomic; Schizocoelomic

Enterocoelomic

 

 

IV.  Phylogenetic Tree Revisited

 

 

 

Animal Skeletal Systems

(Chap. 29; pp. 630-636)

 

 

I.  Selective Forces

            A.  balance between stiffness and strength: 

            B.  weight

            C.  forces of compression and tension

 

II.  Skeletal Materials

A.  connective tissue

B.  cartilage

C.  Bone 

            1.  structure

2.  bone formation 

            a.  cell involved

            b.  types of bone

            c.  hormonal regulattion

D.  Chitin 

 

III.  Skeletal Systems

            A.  Hydrostatic Skeletons

                        1.  Phylum Cnidaria

                                    a.  Polyp

                                    b.  Medusa

                        2.  Phylum Nematoda

                        3.  Phylum Annelida

                        4.  Phylum Mollusca

a.  hemolymph and sinuses

b.  jet propulsion in Cephalopods

                        5.  Phylum Echinodermata: 

a.  water vascular system

b.  tube feet

            B.  Exoskeleton

                        1.  Protozoa

                        2.  Phylum Cnidaria

                        3.  Phylum Mollusca

                        4.  Phylum Arthorpoda

a.  structure of cuticle

                                    b.  use of cuticle to generate movement:  Ex:  flight in insects. 

            1)  structure of thorax segment and wing hinge

2)  indirect flight muscles

·       dorso-ventral muscles

·       dorso-longitudinal muscles

3)  direct flight muscles

 

            C.  Endoskeleton:  skeleton contained within the tissues

                        1.  Porifera

                        2.  Phylum Echinodermata

                        3.  Phylum Chordata

                                    a.  notochord

                                    b.  vertebrate skeleton

1)  axial skeleton

2)  appendicular skeleton

3)  tendons and ligaments

 

 

 

 

Movement Generating Mechanisms

(Chap. 29, pp. 636-646)

 

I.  Selective Forces

 

II.  Amoeboid Movement

 

III.  Cilia and Flagella

            A.  Structure

            B.  Function:  Sliding Microtubule Hypothesis

 

IV.  Muscles

            A.  Types of Muscle Fibers

                        1.  Striated muscle fibers

                                    a.  characteristics

                                    b.  functional types

1)  slow oxidative fibers

2)  fast fibers

·       fast glycolytic fibers

·       fast oxidative fibers

 

2.  Smooth muscle fibers

3.  Cardiac muscle fibers

 

            B.  Muscle structure

                        1.  fasiculus

                        2.  muscle fiber

                                    a.  sarcolemma

                                    b.  sarcoplasmic reticulum

                                    c.  T-tubules

                        3.  myofibrils

                        4.  sarcomere

                                    a.  Z-lines

                                    b.  actin filaments

1)  reactive sites

2)  tropomyosin

3)  troponin

c.  myosin filaments with myosin heads

 

            C.  Sarcomere contraction:  Sliding Filament Hypothesis

 

            D.  Energy for contraction

                        1.  ATP

                        2.  mechanisms for replenishing ATP

                        3.  contraction under anaerobic conditions

 

 

 

Animal Nervous Systems

(Chap. 33)

 

I.  Selective Forces

 

II.  Irritability

 

III.  The Neuron

            A.  Structure: 

a.  neuron components

b.  glial cells

c.  neuronal membrane

            1)  Na+ and K+ channels

            2)  sodium pump

            B.  Types

                        1.  sensory (afferent)

                        2.  motor (efferent

                        3.  interneuron

                        4.  relex arc:  Ex:  reaction to pain (p. 717)

 

            C.  Function

                        1.  Neuron at rest

2.  Action Potential

 

D.  Speed of conduction

1.  axon diameter

                        2.  sheathing

 

            E.  Communication Between Neurons:  the chemical synapse

                        1.  structure

                        2.  function

3.  types of chemical synapses

            a.  excitatory

            b.  inhibitory

4.  summation of synaptic inputs

5.  types of neurotransmitters

6.  Neuromuscular junction

 

III.  Types of Nervous Systems

 

            A.  Nerve net (plexus

            B.  Bilateral Nervous Systems: Invertebrates

                        1.  Phylum Platyhelminthes

                        2.  Phylum Annelida

                        3.  Phylum Arthropoda:  the insect CNS

                                    a.  brain

·       protocerebrum

·       deuterocerebrum

·       tritocerebrum

b.  subesophogael ganglion

c.  ventral nerve cords

d.  segmental ganglia

·       thoracic ganglia

·       abdominal ganglia

e.  hierarchical arrangement of arthropod nervous system 

 

            C.  Bilateral Nervous Systems: Vertebrates

 

                        1.  Spinal Cord

 

                        2.  Brain: 

                                    a.  hindbrain

                                                1)  mylencephalon

·       medulla oblongata

2)  metencephalon:

·       cerebellum:  controls equilibrium, posture and movement; is a precision control center; does not initiate movement

·       pons:  connects two halves of cerebellum and connects medulla and cerebellum to other parts of brain

b.  midbrain:  optic lobes

c.  forebrain:

            1)  diencephalon

·       thalamus

·       hypothalamus

 

2)  telencephalon

·       olfactory lobes (paleocortex

·       cerebrum (neocortex)

 

3.  Peripheral Nervous System:

            a.  somatic nervous system

            b.  autonomic nervous sytem

                        1)  parasympathetic system

                        2)  sympathetic system

 

Animal Sensory Systems

(Chap. 33)

 

I.  Selective Forces

A.  biological transducers

B.  biological transformers

 

II.  Types of Sensory Receptors

            A.  Chemoreception

                        1.  Arthropods:  trichoid sensillum

2.  Mammals

 

            B.  Mechanoreception

                        1.  Hearing

                                    a.  Insects

                                                1)  trichoid sensillum

                                                2)  tympanum

                                    b.  Vertebrate Ear

                                                1)  general structure (p. 728)

                                                2)  cochlea and organ of Corti

                                                3)  function

                        2.  Balance

                                    a.  invertebrates:  statocysts

                                    b.  vertebrates:  labyrinth

                                                1)  saccule and utricle

                                                2)  semicircular canals

 

            C.  Photoreception

                        1.  Simple eyes:  Ocelli

                        2.  Image forming eyes

                                    a.  Compound eye of arthropods

                                                1)  structure of ommatidium

2)  function

b.  Camera eye of vertebrates:

                                                1)  general structure

                                                2)  retina

a)  rod cells

b)  cone cells

                                                3)  biological transformers

a)  lens

b)  tapetum

 

 

 

Chemical Coordination

(Chap. 34)

 

I.  Selective Forces;

 

II.  Hormones:  General Characteristics

            A.  Definition 

            B. Sources of hormones:

                        1.  endocrine glands 

                        2.  exocrine glands

            C.  Effects of hormones

            D.  Interaction of Nervous and Endocrine systems

 

III.  Hormones:  Mechanisms of Action

 

            A.  Receptors

1.  Membrane-bound receptors: 

2.   Nuclear receptors (cytoplasmic receptors)

 

B.  Control of Hormone Secretion

 

 

IV.  Invertebrate Hormones:  Molting and Growth in Insects. 

 

            A.  review of insect cuticle:  epidermis, endocuticle, exocuticle

 

            B.  Hormonal regulation of molting:

1.  prothoracicotropic hormone

2.  ecdysone

3.  eclosion hormone

4.  bursicon

 

            C.  Hormonal regulation of development: 

                        1.  ecdyson

                        2.  juvenile hormone

 

V.  Vertebrate Hormones: 

 

            A.  Central Nervous System regulation of hormones

                        1.  Hypothalamus                    

2.  Pituitary gland

                                    a.  anterior pituitary

1 tropic hormones

o      thyroid stimulating hormone (TSH)

o      follicle stimulating hormone (FSH)

o      luteinizing hormone (LH)

2)  prolactin

3)  growth hormone (GH)

 

b.  posterior pituitary

            1)  oxytocin: 

            2)  vasopressin (anti-diuretic hormone; ADH)

 

 

B.  Hormones and Vertebrate Reproductive cycles:

            1.  Two types of reproductive cycles in females:

                        a.  estrous cycle

                        b.  menstrual cycle

 

            2.  hormonal regulation of menstrual cycle (see attachment):

 

C.  Hormones and Vertebrate Metabolism

            1.  Thyroid hormones: triiodothryronin and thyroxine. 

2.  Adrenal glands: 

§       Glucocorticoids

·       norepinephrine and epinephrine

·       affect water balance (will examine this later)

·       androgens

 


 

Hormonal Regulation of Menstrual Cycle

 

1.  hypothalamus releases GnRH (gonadotropic relasing hormone)

 

2.  GnRH stimulates anterior pituitary to release FHS (follicle stimulating hormone) and LH (luteinizing hormone)

 

3.  FSH causes follicle to form in ovary.  Follicle is endocrine and produces two hormones

·       inhibin:  inhibits FSH release by anterior pituitary (negative feedback)

·       estrogen:  causes the uterine lining to develop

 

4.  after 13-14 days, estrogen reaches a threshold concentration in the blood; causes a surge of LH from anterior pituitary.

 

5.  LH surge causes ovulation and an oocyte is released from the follicle.  Oocyte will live for 12 hours; if not fertilized it will disintegrate.

 

6.  ruptured follicle becomes a scar called the corpus luteum, which is a transitory endocrine gland:

·       is maintained by LH (note: following the LH surge, LH steadily declines back to baseline levels.  Thus, maintenance of the corpus luteum by LH is temporary)

·       releases estrogen and progesterone; finishes preparing the uterus

 

If oocyte is NOT fertilized:

7.  LH declines below level necessary to maintain corpus luteum; corpus luteum degenerates.

 

8.  without corpus luteum, estrogen and progesterone decline below the levels necessary to

maintain lining of uterus

 

9.  menstruation

 

If oocyte IS fertilized:

10.  zygote implants in uterine lining and placenta form; placenta is endocrine

 

11.  placenta produces hCG (human chorionic gonadotropin):

·       maintains corpus luteum and thus uterine lining is not shed (replaces LH in maintaining corpus luteum)

·       placenta begins to produce estrogen and progesterone and maintains uterine lining

·       around the 3rd month of pregnancy, corpus luteum degenerates

 

12.  birth:

·       triggered by a surge in estrogen plus a decline in progesterone

·       uterine contractions maintained by oxytocin from posterior pituitary

 

13.  lactation triggered by prolactin from anterior pituitary

 

 

 

 

Feeding and Digestion

(Chap. 32)

 

I.  Selective Forces

A.  ingestion

B.  digestion

C.  absorption

 

II.  Ingestion (Feed mechanisms)

A.  Feeding on Particulate Matter

 

                        1.  Filter Feeders

                                    a.  Sessile filter feeders:

1)  Porifera

                                                2)  Bivalvia

                                                3)  Barnacles

                                    b.  Mobile filter feeders: 

                                                1)  copepods

                                                2)  flamingo

                                                3)  baleen whales

                        2.  Deposit Feeders

 

B.  Feeding on Food Masses

                        1.  Protozoa

                        2.  Cnidaria

                        3.  Mollusca

                        4.  Crustaceans and Insects

                        5.  Most vertebrates

 

C.  Feeding on Fluids 

                        1.  Plant sap feeders

                        2.  Food liquefiers

                        3.  Blood feeders: 

                                    a.  clotting process:

b.  anticoagulants

 

III.  Digestion

            A.  Site of digestion:

                        1.  intracellular 

                        2.  extracellular 

                        3.  intracellular and extracellular digestion

 

            B.  Mechanical breakdown of food

                        1.  mouthparts

                                    a.  radula of mollusks

                                    b.  mandibles of arthropods

                                    c.  vertebrate teeth

                                                1)  homodont dentition

2)  heterodont dentition

2.  internal grinding devices

            a.  gizzard

            b.  gastric mill of crustaceans

 

            C.  Chemical breakdown of food:  digestive enzymes

                        1.  Hydrolysis: 

                                    R-R + H2O  digestive enzymeà R-OH + H-R

 

                        2.  Chemical digestion in higher vertebrates

Source of Enzymes

Secretions and Enzymes

Function

Salivary glands

Salivary amylase

Converts starch into maltose

Stomach

·        HCl

 

·        pepsin (secreted as pepsinogen)

·        creates acidic environment for protein digestion

·        breaks proteins into smaller polypeptides

·        results in chyme, which moves into dueodenum

Duodenum of small intestines

1.  for digestion of carbohydrates

·        pancreatic amylase

 

2.  for digestion of proteins

·        trypsin

·        chymotrypsin

·        carboxypeptidase

 

3.  for digestion of lipids

·        bile

·        pancreatic lipase

 

·        starch à maltose

 

 

·        polypeptides à amino acids

 

 

 

 

·        from liver; emulsifies fats and oils

·        breaks down fats and oils

                                   

3.  Hormonal regulation of digestive enzymes

            a.  gastrin

b.  cholecystokinin (CCK)

c.  secretin

 

                        4.  Chemical digestion in herbivores

 

IV.  Absorption 

            A.  Incomplete gut

            B.  Complete gut

                        1.  typhlosole of annelids

                        2.  digestive glands of arthropods

                        3.  vertebrate small intestines:  villi and microvilli

 

 

 

 

Homeostatis and Water Balance

(Chap. 30)

 

 

I.  Selective Forces

            A.  Osmoregulation

            B.  Elimination of nitrogenous wastes

 

II.  Osmoregulation

            A.  Terminology

                        1.  osmotic pressure

                        2.  isosmotic

                        3.  hyperosmotic

                        4.  hypoosmotic

                        5.  osmoconformer

                        6.  osmoregulator

            B.  Osmoregulation in Marine Environments

                        1.  Estuarine invertebrates

                        2.  Chondrichthyes

                        3.  Marine Osteichthyes

            C.  Osmoregulation in Freshwater Environments

            D.  Osmoregulation Terrestrial Environments

 

III.  Elimination of Nitrogenous Wastes

            A.  Source of nitrogenous wastes

            B.  Forms of nitrogenous wastes

                        1.  ammonia

                        2.  urea

                        3.  uric acid

                        4.  guanine

 

IV.  Excretory and Osmoregulatory Mechanisms

            A.  Contractile vacuoles

            B.  Body surface

            C.  Excretory organs

                        1.  Protonephridia of Platyhelminthes

                                    a.  structure

                                    b.  function

                        2.  Metanephridia of Annelids

                                    a.  structure

                                    b.  function

                        3.  Malpighian tubule/Hindgut system of Insects

                                    a.  structure

                                    b.  function

                                                1)  filtration

                                                2)  reabsorbtion and secretion

                                                3)  hormonal regulation

·       diuretic hormone

·       antidiuretic hormone

·       proctolin

 

4.  Vertebrate Kidney

            a.  general structure

            b.  structure of nephron

            c.  function of nephron

                        1)  filtration

                        2)  tubular reabsorbtion

                        3)  tubular secretion

                        4)  water balance and formation of concentrated urine

                                    a)  ascending limb of Loop of Henle

                                    b)  descending limb of Loop of Henle

                                    c)  collecting duct

            d.  hormonal control of nephron

                        1)  ADH

                        2)  Juxtaglomerular appartus

·       rennin

·       angiotensin

o      aldosterone

o      ADH

o      blood pressure

o      thirst

 

 

 

 

Gas Exchange and Respiration

(Chap. 31)

 

 

I.  Selective Forces:

            A.  Problems associated with diffusion:

                        1.  expose moist body surface            

2.  Limitations to diffusion

                                    a.  surface area

                                    b.  partial pressure of gas                               

c.  surface/volume ratio

 

            B.  General mechanisms for increasing uptake of oxygen

                        1.  countercurrent exchange systems                           

a.  concurrent exchange

                                    b.  counter current exchang3

                        2.  respiratory pigments

                                    a.  Types

                                                1)  hemocyanin

                                                2)  hemoglobin

                                                3)  myoglobin

                                    b.  Factors affecting hemoglobin affinity for O2

                                                1)  partial pressure of O2

                                                2)  cooperativity

                                                3)  pH

                                               

 

II.   Respiration in Aquatic Envrionments:

            A.  The environment

            B.  Respiratory mechanisms

1.  Body surface

                        2.  Molluscs

                        3.  Crustaceans:  gills and gill bailer

                        4.  Echinoderms:  dermal branchia

                        5.  Fish gills

 

 

III.  Respiration in Terrestrial Environment

            A.  The environment

            B.  Respiratory mechanisms

                        1.  diffusion across body surface

                        2.  Modified gills of crustaceans:  pill bugs (Isopods)

                        3.  Trachea

                                    a.  structure

                                    b.  function

                                    c.  ventilation

4.  Lungs

                                    a.  diffusion lungs

                                                -- Pulmonate snails

                                                -- book lungs of arachnids

 

                                    b.  ventilation lungs:  mammals

                                                1)  structure

                                                2)  ventilation

·        inhalation

·        exhalation

3)  regulation of breathing

 

 

                                    c.  ventilation lungs:  birds

                                                1)  structure

2)  air flow

·        inhalation 1

·        exhalation 1

·        inhalation 2

·        exhalation 2

 

 

 

 

 

Body Fluids and Circulatory Systems

(Chap. 31)

 

I.  Selective Forces 

II.  Circulatory Mechanisms

            A.  Circulation without circulatory system

                        1.  Protozoa                

2.  Porifera 

                        3.  Circulation via gastrovascular cavity

                                    a.  Cnidaria

                                    b.  Platyhelminthes

                        4.  Circulation via coelom

                                    a.  Nematoda

                                    b.  Echinoderms

            B.  Circulation with an open circulatory system

                        1.  Characteristics of open system: 

                        2.  Molluscs

                        3.  Insects

            C.  Circulation with a closed circulatory system:  Invertebrates

                        1.  characteristics

                        2.  Annelids

3.  Cephalopods: 

a.  branchial circuit 

b.  systemic circuit 

            D.  Circulation with closed system:  Vertebrates 

1.  arteries and veins

2.  evolution of vertebrate circulatory system: 

3.  Osteichthyes

                                    a.  structure     

                                    b.  blood flow

                        4.  Reptiles

a.  structure:

b.  blood flow

            pulmonary circuit

            systemic circuit

c.  comparison of fish and reptilian system:

 

Fish

Reptile

 

One-way flow

Two circuit flow

2 chambered heart

3 chambered heart with incomplete septum

Bulbous arteriosus

Pulmonary artery, 2 systemic arches

Sinus venosus

Sinatrial node (pace maker)

 

d.  function of incomplete septum: 

1) hibernation

2) diving

5.  Mammals and Birds 

            a.  structure     

b.  blood flow:

                        pulmonary circuit

                        systemic circuit

c.  comparison of reptilian and mammalian system

 

Reptile

Mammal and Birds

 

Two circuit flow

Two circuit flow

3 chambered heart with incomplete septum

4 chambered heart with

complete septum

Pulmonary artery; 2 systemic arches

Pulmonary artery, aortic arch

Sinatrial node (pace maker)

Sinatrial node (pace maker)

 

 

                                    d.  regulation of heart beat and blood pressure

                                                1) rhythmicity of heart beat

2)  blood pressure

 

           

 

Immunity (Chap. 35)

I.  Selective Forces

 

II.  Types of Immunity

               A.  Acquired immunity

                        1.  humoral immune response

                        2.  cell mediated immune response

               B.  Innate immunity

 

 

III.  Cells of the Immune System

               A.  Phagocytes

                        1.  function

                        2.  macrophages

                                    a.  mononuclear phagocyte system

                                    b.  polymorphonuclear leukocytes

               B.  Leukocytes

                        1.  B cells

                                    a.  plasma cells

                                    b. memory B cells

                        2.  T cells

                                    a.  T helper cells

                                    b.  Cytotoxic T lymphocytes

                                    c.  T-suppressor cells

                                    d.  T-memory cells

               C.  Mast cells

               D.  Natural Killer cells

 

IV.  Complement

               A.  classical pathway

               B.  alternate pathway

                       

 

V.  Basis of Self/Non-self Recognition

               A.  Major Histocompatibility Complex (MHC)

               B.  Types of MHC proteins

                        1.  MHC class I

                        2.  MHC class II           

                       

VI.  Recognition Molecules

               Aantibodies (Ab)

                        1.  structure

                        2.  function

               B.  T-cell receptors

                        1.  structure

                        2.  function 

 

VII.  Acquired immune response

               A.  Humoral immune response

               B.  Cell mediated immune response

               C.  Inflammation

                        1.  Delayed type hypersensitivity

                        2.  Immediate hypersensitivity

 

VIII.  Innate immune response

               A.  Physical barriers

               B.  Chemical barriers